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Genre/Form: | Electronic books |
---|---|
Additional Physical Format: | Print version: |
Material Type: | Document, Internet resource |
Document Type: | Internet Resource, Computer File |
All Authors / Contributors: |
Thomas D Pollard; William C Earnshaw; Jennifer Lippincott-Schwartz |
ISBN: | 9781437700633 1437700632 |
OCLC Number: | 861538874 |
Description: | 1 online resource (927 pages) |
Contents: | Front Cover -- Cell Biology -- Copyright Page -- Instructions for online access -- Contents -- Contributors -- Preface to the Second Edition -- Preface to the First Edition -- Acknowledgments -- SECTION I: Introduction to Cell Biology -- Chapter 1. Introduction to Cells -- Features That DistinguishEukaryotic and ProkaryoticCells -- Some Universal Principles ofLiving Cells -- Overview of Eukaryotic Cellular Organization and Functions -- Chapter 2. Evolution of Life on Earth -- Prebiotic Chemistry Leading to anRNA World -- Divergent Evolution from the LastUniversal Common Ancestor of Life ATP-Driven Pumps -- Chapter 9. Membrane Carriers -- Diversity of Carrier Proteins -- Structure of MFS Carrier Proteins -- Carrier Physiology and Mechanisms -- Chapter 10. Membrane Channels -- Channel Diversity and Evolution -- Channel Structure -- Channel Activity -- Channels with OneTransmembrane Segment -- Channels with TwoTransmembrane Segments -- Channels with FourTransmembrane Helices -- Voltage-Gated Cation Channels -- TRP Channels -- Channels Gated byIntracellular Ligands -- Ion Channels Gated byExtracellular Ligands -- ClC Chloride Channels -- Ammonia Channels -- Water Channels -- Porins Evolution of Prokaryotes -- Origin of Eukaryotes -- Origin and Evolution of Mitochondria -- The First Billion Years ofEukaryotic Evolution -- Origins and Evolutionof Chloroplasts -- Evolution of Multicellular Eukaryotes -- Looking Back in Time -- SECTION II: Chemical and Physical Background -- SECTION II OVERVI EW -- Chapter 3. Molecules: Structures and Dynamics -- Proteins -- Nucleic Acids -- Carbohydrates -- The Aqueous Phase of Cytoplasm -- Chapter 4. Biophysical Principles -- First-Order Reactions -- Second-Order Reactions -- Reversible Reactions -- Thermodynamic Considerations Inventory: Gene andProtein Discovery -- Molecular Structure -- Partners and Pathways -- Rates and Affinities -- Tests of Physiological Function -- Mathematical Models of Systems -- SECTION III: Membrane Structureand Function -- SECTION III OVER VIEW -- Chapter 7. Membrane Structureand Dynamics -- Development of Ideas about Membrane Structure -- Lipids -- Physical Structure of the FluidMembrane Bilayer -- Membrane Proteins -- Chapter 8. Membrane Pumps -- Membrane Permeability:An Introduction -- Membrane Pumps -- Diversity of Membrane Pumps -- Light-Driven Proton Pumpingby Bacteriorhodopsin Linked Reactions -- Chemical Bonds -- A Strategy for UnderstandingCellular Functions -- Analysis of an Enzyme Mechanism:The Ras GTPase -- Chapter 5. Macromolecular Assembly -- Assembly of MacromolecularStructures from Subunits -- Specificity by Multiple Weak Bondson Complementary Surfaces -- Symmetrical StructuresConstructed from IdenticalSubunits with Equivalent(or Quasi-equivalent) Bonds -- New Properties from Sequential Assembly Pathways -- Regulation at Multiple Steps onSequential Assembly Pathways -- Chapter 6. Research Strategies -- Imaging -- Choice of Organisms forBiological Research |
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Abstract:
A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the ""hardware"" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures. Covers essential concepts in a.

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